2022 Berkeley Tennis Club Challenge – Singles

Usue Maitane Arconada was the defending champion but chose not to participate.

Madison Brengle won the title, defeating Yuan Yue in the final, 6–7(3–7), 6–3, 6–2.

Seeds
• # 🇺🇸 Madison Brengle (champion)

• # 🇨🇳 Yuan Yue (final)

• # 🇺🇸 Katie Volynets (second round)

• # 🇧🇪 Greet Minnen (first round)

• # 🇺🇸 Robin Anderson (second round)

• # 🇺🇸 Sachia Vickery (second round, retired)

• # 🇺🇸 Katrina Scott (first round)

• # 🇺🇸 Louisa Chirico (semifinals)