2022 Birmingham Classic – Singles

Beatriz Haddad Maia won the women's singles title at the 2022 Birmingham Classic, after Zhang Shuai retired from the final with the scoreline at 5–4 due to a neck injury. By winning the title, Haddad Maia extended her winning streak to 10 consecutive matches.

Ons Jabeur was the defending champion, but she chose to play in Berlin instead.

Seeds
• # Jeļena Ostapenko (second round)

• # 🇷🇴 Simona Halep (semifinals)

• # 🇮🇹 Camila Giorgi (quarterfinals)

• # 🇧🇪 Elise Mertens (first round)

• # 🇨🇿 Petra Kvitová (first round)

• # 🇷🇴 Sorana Cîrstea (semifinals)

• # 🇺🇸 Alison Riske (first round)

• # 🇨🇳 Zhang Shuai (final, retired)

Seeds
• # Donna Vekić (qualified)

• # 🇷🇸 Aleksandra Krunić (qualifying competition, lucky loser)

• # 🇨🇦 Rebecca Marino (qualified)

• # 🇺🇦 Lesia Tsurenko (qualified)

• # 🇺🇸 CoCo Vandeweghe (qualified)

• # 🇦🇺 Maddison Inglis (qualifying competition)

• # 🇪🇸 Cristina Bucșa (qualifying competition)

• # 🇵🇱 Katarzyna Kawa (first round)

• # 🇦🇺 Astra Sharma (first round)

• # 🇨🇳 Wang Qiang (moved to main draw)

• # 🇷🇴 Gabriela Lee (qualifying competition)

• # 🇲🇽 Fernanda Contreras (qualifying competition)

Qualifiers
• # Donna Vekić

• # Jana Fett

• # 🇨🇦 Rebecca Marino

• # 🇺🇦 Lesia Tsurenko

• # 🇺🇸 CoCo Vandeweghe

• # 🇺🇸 Caty McNally

Lucky loser
• # 🇷🇸 Aleksandra Krunić