2022 Challenger Ciudad de Guayaquil – Doubles

Jesper de Jong and Bart Stevens were the defending champions but only de Jong chose to defend his title, partnering Max Houkes. De Jong and Houkes retired from their first round match against Boris Arias and Federico Zeballos.

Guido Andreozzi and Guillermo Durán won the title after defeating Facundo Díaz Acosta and Luis David Martínez 6–0, 6–4 in the final.

Seeds
• # 🇮🇳 Sriram Balaji / 🇮🇳 Jeevan Nedunchezhiyan (semifinals)

• # 🇦🇷 Guido Andreozzi / 🇦🇷 Guillermo Durán (champions)

• # 🇧🇴 Boris Arias / 🇧🇴 Federico Zeballos (quarterfinals)

• # 🇦🇷 Facundo Díaz Acosta / 🇻🇪 Luis David Martínez (final)