2022 Challenger de Tigre II – Singles

Santiago Rodríguez Taverna was the defending champion but lost in the quarterfinals to Genaro Alberto Olivieri.

Camilo Ugo Carabelli won the title after defeating Andrea Collarini 7–5, 6–2 in the final.

Seeds
• # 🇦🇷 Facundo Bagnis (second round)

• # 🇵🇪 Juan Pablo Varillas (semifinals)

• # 🇦🇷 Camilo Ugo Carabelli (champion)

• # 🇦🇷 Renzo Olivo (second round)

• # 🇧🇷 Felipe Meligeni Alves (quarterfinals)

• # 🇦🇷 Nicolás Kicker (first round)

• # 🇦🇷 Santiago Rodríguez Taverna (quarterfinals)

• # 🇧🇷 João Menezes (first round)