2022 Challenger di Roseto degli Abruzzi – Singles

This was the first edition of the tournament.

Carlos Taberner won the title after defeating Nuno Borges 6–2, 6–3 in the final.

Seeds
• # 🇪🇸 Carlos Taberner (champion)

• # 🇮🇹 Stefano Travaglia (first round, withdrew)

• # 🇪🇸 Bernabé Zapata Miralles (second round)

• # 🇷🇸 Nikola Milojević (second round)

• # 🇸🇰 Andrej Martin (first round)

• # Nuno Borges (final)

• # 🇮🇹 Flavio Cobolli (semifinals)

• # 🇮🇹 Gian Marco Moroni (first round)