2022 Christus Health Pro Challenge – Singles

Misaki Doi was the defending champion but chose to compete at the 2022 Torneig Internacional Els Gorchs instead.

Taylor Townsend won the title, defeating Yuan Yue in the final, 6–4, 6–2.

Seeds
• # 🇪🇪 Kaia Kanepi (first round)

• # 🇺🇸 Madison Brengle (first round)

• # 🇭🇺 Panna Udvardy (second round)

• # 🇨🇳 Yuan Yue (final)

• # 🇺🇸 Katie Volynets (second round)

• # 🇷🇴 Gabriela Lee (first round)

• # 🇲🇽 Marcela Zacarías (first round)

• # 🇦🇷 María Lourdes Carlé (quarterfinals)