2022 City of Playford Tennis International – Women's singles

Storm Sanders was the defending champion but chose to compete at the 2022 Christus Health Pro Challenge instead.

Kimberly Birrell won the title, defeating Maddison Inglis in the final, 3–6, 7–5, 6–4.

Seeds
• # 🇦🇺 Priscilla Hon (quarterfinals)

• # 🇦🇺 Jaimee Fourlis (quarterfinals)

• # 🇦🇺 Maddison Inglis (final)

• # 🇰🇷 Han Na-lae (semifinals)

• # 🇦🇺 Olivia Gadecki (quarterfinals)

• # 🇦🇺 Kimberly Birrell (champion)

• # 🇦🇺 Lizette Cabrera (semifinals)

• # 🇯🇵 Mai Hontama (quarterfinals)