2022 Columbus Challenger II – Singles

Yoshihito Nishioka was the defending champion but chose not to defend his title.

Jordan Thompson won the title after defeating Emilio Gómez 7–6(8–6), 6–2 in the final.

Seeds
• # 🇦🇺 Jordan Thompson (champion)

• # 🇪🇨 Emilio Gómez (final)

• # Dominic Stricker (quarterfinals)

• # 🇦🇺 Aleksandar Vukic (quarterfinals)

• # 🇫🇷 Enzo Couacaud (second round)

• # 🇩🇪 Dominik Koepfer (first round)

• # 🇬🇧 Paul Jubb (second round)

• # 🇦🇺 Rinky Hijikata (semifinals)