2022 Corrientes Challenger – Singles

Máximo González was the defending champion when the event was last held in 2015, but he chose not to defend his title.

Francisco Comesaña won the title after defeating Mariano Navone 6–0, 6–3 in the final.

Seeds
• # 🇦🇷 Juan Pablo Ficovich (semifinals)

• # 🇦🇷 Francisco Comesaña (champion)

• # 🇨🇴 Nicolás Mejía (first round)

• # 🇦🇷 Gonzalo Villanueva (first round)

• # 🇩🇴 Nick Hardt (quarterfinals)

• # 🇹🇳 Malek Jaziri (first round)

• # 🇦🇷 Facundo Juárez (second round)

• # 🇵🇪 Nicolás Álvarez (first round)