2022 Credit One Charleston Open – Singles

Belinda Bencic defeated Ons Jabeur in the final, 6–1, 5–7, 6–4, to win the singles tennis title at the 2022 Charleston Open. Her victory made her the first Swiss player to win the title since Martina Hingis in 1999 and earned her the distinction of holding titles across all three major surfaces.

Veronika Kudermetova was the defending champion, but she withdrew before the tournament began.

Seeds
The top eight seeds received a bye into the second round. • Aryna Sabalenka (third round)

• 🇪🇸 Paula Badosa (quarterfinals)

• 🇨🇿 Karolína Plíšková (third round)

• 🇹🇳 Ons Jabeur (final)

• 🇰🇿 Elena Rybakina (second round)

• 🇺🇸 Jessica Pegula (third round)

• 🇨🇦 Leylah Fernandez (second round)

• Veronika Kudermetova (withdrew)

• 🇺🇸 Madison Keys (third round)

• Belinda Bencic (champion)

• 🇨🇿 Petra Kvitová (first round, retired)

• 🇫🇷 Alizé Cornet (third round)

• 🇺🇸 Sloane Stephens (first round)

• 🇦🇺 Ajla Tomljanović (second round)

• 🇺🇸 Amanda Anisimova (semifinals)

• 🇨🇳 Zhang Shuai (second round)

Seeds
• # 🇬🇧 Heather Watson (qualifying competition, lucky loser)

• # 🇺🇸 Christina McHale (first round)

• # 🇺🇸 CoCo Vandeweghe (qualifying competition, lucky loser)

• # 🇺🇸 Robin Anderson (qualified)

• # 🇺🇸 Caroline Dolehide (first round)

• # 🇺🇸 Grace Min (qualifying competition)

• # 🇺🇸 Jamie Loeb (qualifying competition)

• # 🇺🇸 Francesca Di Lorenzo (qualified)

• # 🇲🇽 Marcela Zacarías (first round)

• # 🇺🇸 Sachia Vickery (qualified)

• # 🇷🇴 Gabriela Lee (qualified)

• # 🇺🇸 Whitney Osuigwe (first round)

• # 🇺🇸 Allie Kiick (qualified)

• # 🇺🇸 Catherine Harrison (qualifying competition)

• # 🇳🇴 Ulrikke Eikeri (qualified)

• # 🇨🇦 Carol Zhao (qualifying competition)

Qualifiers
• # 🇳🇴 Ulrikke Eikeri

• # 🇺🇦 Nadiia Kichenok

• # 🇷🇴 Gabriela Lee

• # 🇺🇸 Robin Anderson

• # 🇺🇸 Sophie Chang

• # 🇺🇸 Sachia Vickery

• # 🇺🇸 Allie Kiick

• # 🇺🇸 Francesca Di Lorenzo

Lucky losers
• # 🇬🇧 Heather Watson

• # 🇺🇸 CoCo Vandeweghe