2022 Eastbourne International – Women's singles

Petra Kvitová defeated the defending champion Jeļena Ostapenko in the final, 6–3, 6–2 to win the women's singles tennis title at the 2022 Eastbourne International. Ostapenko was aiming to be the first woman to defend the Eastbourne title since Justine Henin in 2007.

Seeds
All seeds received a bye into the second round. • 🇪🇸 Paula Badosa (second round)

• 🇹🇳 Ons Jabeur (withdrew)

• Maria Sakkari (second round)

• 🇨🇿 Karolína Plíšková (second round)

• 🇪🇸 Garbiñe Muguruza (third round)

• 🇺🇸 Coco Gauff (withdrew)

• 🇨🇿 Barbora Krejčíková (second round)

• Jeļena Ostapenko (final)

• 🇰🇿 Elena Rybakina (second round)

• Jil Teichmann (second round)

• 🇺🇸 Madison Keys (third round, retired)

• 🇮🇹 Camila Giorgi (semifinals)

• 🇧🇪 Elise Mertens (second round)

• 🇨🇿 Petra Kvitová (champion)

• 🇧🇷 Beatriz Haddad Maia (semifinals)

• 🇰🇿 Yulia Putintseva (third round)

• 🇺🇸 Alison Riske (second round)

Seeds
• # Donna Vekić (qualified)

• # 🇨🇳 Wang Xiyu (withdrew)

• # 🇬🇧 Heather Watson (qualifying competition, lucky loser)

• # 🇷🇸 Aleksandra Krunić (qualified)

• # 🇦🇺 Daria Saville (first round)

• # 🇨🇦 Rebecca Marino (qualifying competition, lucky loser)

• # 🇫🇷 Kristina Mladenovic (first round)

• # 🇺🇦 Lesia Tsurenko (qualified)

Qualifiers
• # Donna Vekić

• # 🇧🇪 Kirsten Flipkens

• # 🇺🇦 Lesia Tsurenko

• # 🇷🇸 Aleksandra Krunić

Lucky losers
• # 🇨🇦 Rebecca Marino

• # 🇬🇧 Heather Watson

• # 🇧🇬 Viktoriya Tomova