2022 Emilia-Romagna Open – Men's singles

Sebastian Korda was the defending champion but chose not to defend his title.

Borna Ćorić won the title after defeating Elias Ymer 7–6(7–4), 6–0 in the final.

Seeds
• # 🇦🇷 Federico Coria (first round)

• # 🇷🇸 Dušan Lajović (semifinals)

• # 🇧🇴 Hugo Dellien (withdrew)

• # 🇦🇷 Tomás Martín Etcheverry (second round)

• # 🇪🇸 Carlos Taberner (second round)

• # 🇪🇸 Roberto Carballés Baena (first round)

• # 🇪🇸 Bernabé Zapata Miralles (first round)

• # 🇧🇷 Thiago Monteiro (second round)