2022 FINA World Swimming Championships (25 m) – Women's 100 metre individual medley

The Women's 100 metre individual medley competition of the 2022 FINA World Swimming Championships (25 m) was held on 15 and 16 December 2022.

Records
Prior to the competition, the existing world and championship records were as follows.

Heats
The heats were started on 15 December at 12:02.

Semifinals
The semifinals were started on 15 December at 20:57.

Final
The final was held on 16 December at 20:56.