2022 FineMark Women's Pro Tennis Championship – Singles

Katie Volynets was the defending champion but retired in the semifinals against Gabriela Lee.

Lee went on to win the title, defeating Katarzyna Kawa in the final, 6–1, 6–3.

Seeds
• # 🇷🇴 Irina Bara (quarterfinals)

• # 🇩🇪 Tatjana Maria (second round)

• # 🇺🇸 Katie Volynets (semifinals, retired)

• # 🇨🇳 Wang Xiyu (semifinals)

• # 🇺🇸 CoCo Vandeweghe (first round, retired)

• # 🇸🇪 Mirjam Björklund (first round)

• # 🇵🇱 Katarzyna Kawa (final)

• # 🇷🇴 Alexandra Cadanțu-Ignatik (quarterfinals)