2022 Grand Est Open 88 – Singles

Anhelina Kalinina was the defending champion but chose not to participate.

Sara Errani won the title, defeating Dalma Gálfi in the final, 6–4, 1–6, 7–6(7–4).

Seeds
• # 🇭🇺 Anna Bondár (semifinals)

• # Varvara Gracheva (first round)

• # 🇮🇹 Jasmine Paolini (quarterfinals)

• # 🇫🇷 Océane Dodin (first round)

• # Arantxa Rus (second round)

• # 🇭🇺 Dalma Gálfi (final)

• # Ylena In-Albon (first round)

• # 🇺🇸 Katie Volynets (first round)

Seeds
• # Erika Andreeva (qualified)

• # Natalia Vikhlyantseva (qualifying competition, retired)

• # 🇮🇹 Camilla Rosatello (qualified)

• # 🇫🇷 Alice Robbe (qualified)

Qualifiers
• # Erika Andreeva

• # 🇩🇪 Lena Papadakis

• # 🇮🇹 Camilla Rosatello

• # 🇫🇷 Alice Robbe