2022 Guadalajara Open Akron

In 2022, the WTA calendar was still being affected by the cancellation of women's professional tennis tournaments in China and Russia due to the COVID-19 pandemic, the Russian invasion of Ukraine, and concerns about the security and well-being of tennis player Peng Shuai after her allegations of sexual assault against Chinese Communist Party leader Zhang Gaoli. As a result, a WTA 1000 tournament was announced to be held in Guadalajara to compensate for it. This was one of the biggest women's tournaments ever hosted by Mexico, held on outdoor hard courts in October 2022.

Singles

 * 🇺🇸 Jessica Pegula def. Maria Sakkari, 6–2, 6–3

This is Pegula's first title of the year and second of her career.

Doubles

 * 🇦🇺 Storm Sanders / 🇧🇷 Luisa Stefani def. 🇰🇿 Anna Danilina / 🇧🇷 Beatriz Haddad Maia 7–6(7–4), 6–7(2–7), [10–8]

Prize money

 * per team

Seeds
† Rankings are as of 10 October 2022.

Other entrants
The following players received wildcards into the main draw:
 * 🇨🇦 Eugenie Bouchard
 * 🇲🇽 Fernanda Contreras Gómez
 * Donna Vekić

The following player received entry into the singles main draw with a protected ranking:
 * 🇨🇦 Bianca Andreescu

The following players received entry from the qualifying draw:
 * 🇮🇹 Elisabetta Cocciaretto
 * 🇺🇸 Lauren Davis
 * 🇺🇸 Kayla Day
 * 🇺🇸 Caroline Dolehide
 * 🇵🇱 Magdalena Fręch
 * 🇨🇿 Linda Fruhvirtová
 * 🇨🇦 Rebecca Marino
 * 🇺🇸 Asia Muhammad

The following players received entry as lucky losers:
 * Elina Avanesyan
 * 🇯🇵 Nao Hibino
 * 🇧🇷 Laura Pigossi

Withdrawals

 * Before the tournament
 * 🇺🇸 Amanda Anisimova → replaced by 🇺🇸 Sloane Stephens
 * 🇺🇸 Sofia Kenin → replaced by 🇺🇸 Ann Li
 * 🇪🇪 Anett Kontaveit → replaced by Anna Kalinskaya
 * Petra Martić → replaced by 🇵🇱 Magda Linette
 * 🇪🇸 Garbiñe Muguruza → replaced by 🇺🇦 Marta Kostyuk
 * 🇺🇸 Shelby Rogers → replaced by 🇯🇵 Nao Hibino
 * 🇺🇸 Alison Riske-Amritraj → replaced by 🇧🇷 Laura Pigossi
 * 🇨🇳 Zhang Shuai → replaced by Elina Avanesyan
 * 🇨🇳 Zheng Qinwen → replaced by 🇨🇿 Tereza Martincová

Seeds

 * 1 Rankings as of 10 October 2022.

Other entrants
The following pairs received wildcards into the doubles main draw:
 * Victoria Azarenka / 🇺🇸 Bethanie Mattek-Sands
 * 🇲🇽 Fernanda Contreras Gómez / 🇨🇴 Camila Osorio
 * 🇺🇸 Caroline Dolehide / 🇺🇸 CoCo Vandeweghe

The following pairs received entry as alternates:
 * 🇮🇹 Elisabetta Cocciaretto / 🇮🇹 Martina Trevisan
 * 🇺🇦 Marta Kostyuk / 🇨🇿 Tereza Martincová

Withdrawals

 * 🇭🇺 Anna Bondár / 🇧🇪 Kimberley Zimmermann → replaced by 🇺🇦 Nadiia Kichenok / 🇧🇪 Kimberley Zimmermann
 * 🇺🇸 Caroline Dolehide / 🇺🇸 CoCo Vandeweghe → replaced by 🇺🇦 Marta Kostyuk / 🇨🇿 Tereza Martincová
 * 🇺🇸 Asia Muhammad / 🇨🇳 Zhang Shuai → replaced by 🇮🇹 Elisabetta Cocciaretto / 🇮🇹 Martina Trevisan