2022 Hamburg Ladies & Gents Cup – Men's singles

Taro Daniel was the defending champion but chose not to defend his title.

Alexander Ritschard won the title while leading 7–5, 6–5 after Henri Laaksonen retired in the final.

Seeds
• # 🇫🇷 Grégoire Barrère (quarterfinals)

• # Jelle Sels (quarterfinals)

• # 🇦🇹 Dennis Novak (first round)

• # Alexander Ritschard (champion)

• # Henri Laaksonen (final, retired)

• # 🇹🇷 Altuğ Çelikbilek (first round)

• # 🇨🇿 Jonáš Forejtek (quarterfinals)

• # 🇺🇦 Oleksii Krutykh (first round)