2022 I.ČLTK Prague Open

The 2022 I.ČLTK Prague Open was a tournament played on outdoor clay. It was the 29th edition for men and 17th for women, which were respectively part of the 2022 ATP Challenger Tour and the 2022 ITF Women's World Tennis Tour. It took place in Prague, Czech Republic between 2 and 8 May 2022.

Seeds

 * 1 Rankings are as of 25 April 2022.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇨🇿 Jonáš Forejtek
 * 🇨🇿 Martin Krumich
 * 🇨🇿 Andrew Paulson

The following player received entry into the singles main draw using a protected ranking:
 * 🇦🇹 Sebastian Ofner

The following player received entry into the singles main draw as a special exempt:
 * 🇫🇷 Evan Furness

The following player received entry into the singles main draw as an alternate:
 * 🇺🇦 Illya Marchenko

The following players received entry from the qualifying draw:
 * 🇮🇹 Matteo Donati
 * 🇩🇪 Lucas Gerch
 * 🇵🇱 Daniel Michalski
 * 🇮🇱 Yshai Oliel
 * 🇨🇿 Lukáš Rosol
 * 🇫🇷 Clément Tabur

The following players received entry as lucky losers:
 * 🇦🇺 Max Purcell
 * 🇯🇵 Kaichi Uchida

Seeds

 * 1 Rankings are as of 25 April 2022.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇨🇿 Lucie Havlíčková
 * 🇨🇿 Miriam Kolodziejová
 * 🇺🇦 Daria Lopatetska
 * 🇨🇿 Barbora Palicová

The following player received entry using a protected ranking:
 * 🇦🇺 Priscilla Hon

The following player received entry as a special exempt:
 * 🇨🇿 Nikola Bartůňková

The following players received entry from the qualifying draw:
 * 🇨🇿 Anastasia Dețiuc
 * 🇯🇵 Nagi Hanatani
 * 🇨🇿 Linda Klimovičová
 * 🇨🇿 Aneta Laboutková
 * 🇩🇪 Luisa Meyer auf der Heide
 * 🇷🇴 Andreea Prisăcariu
 * 🇨🇿 Dominika Šalková
 * 🇷🇸 Natalija Stevanović

The following player received entry as a lucky loser:
 * 🇲🇽 Ana Sofía Sánchez

Men's singles

 * 🇦🇷 Pedro Cachin def. 🇮🇹 Lorenzo Giustino 6–3, 7–6(7–4).

Men's doubles

 * Nuno Borges / Francisco Cabral def. 🇨🇿 Andrew Paulson / 🇨🇿 Adam Pavlásek 6–4, 6–7(3–7), [10–5].

Women's singles

 * 🇵🇱 Maja Chwalińska def. Ekaterine Gorgodze, 7–5, 6–3

Women's doubles

 * Bárbara Gatica / 🇧🇷 Rebeca Pereira def. 🇨🇿 Miriam Kolodziejová / 🇨🇿 Jesika Malečková, 6–4, 6–2