2022 I.ČLTK Prague Open – Men's doubles

The men's doubles of the 2022 I.ČLTK Prague Open tournament took place on clay in Prague, Czech Republic.

Marc Polmans and Sergiy Stakhovsky were the winners of the last edition but did not defend their title. Polmans chose not to participate, while Stakhovsky retired at the beginning of 2022.

Nuno Borges and Francisco Cabral won the title after defeating Andrew Paulson and Adam Pavlásek 6–4, 6–7(3–7), [10–5] in the final.

Seeds
• # 🇨🇿 Roman Jebavý / Matwé Middelkoop (first round)

• # 🇫🇷 Sadio Doumbia / 🇫🇷 Fabien Reboul (quarterfinals)

• # Nuno Borges /  Francisco Cabral (champions)

• # 🇺🇸 Nicholas Monroe / 🇧🇷 Fernando Romboli (semifinals)