2022 Internazionali Femminili di Palermo

The 2022 Internazionali Femminili di Palermo was a professional women's tennis tournament played on outdoor clay courts at the Country Time Club. It was the 30th edition of the tournament and part of the 2022 WTA Tour. It took place in Palermo, Italy, between 18 and 24 July 2022.

Singles

 * 🇷🇴 Irina-Camelia Begu def. 🇮🇹 Lucia Bronzetti 6–2, 6–2

This was Begu's first title of the year and fifth of her career.

Doubles

 * 🇭🇺 Anna Bondár / 🇧🇪 Kimberley Zimmermann def. Amina Anshba / 🇭🇺 Panna Udvardy 6–3, 6–2.

Seeds

 * † Rankings are as of 11 July 2022

Other entrants
The following players received wildcards into the main draw:
 * 🇮🇹 Elisabetta Cocciaretto
 * 🇮🇹 Sara Errani
 * 🇮🇹 Lucrezia Stefanini

The following player received entry using a protected ranking:
 * 🇩🇪 Laura Siegemund

The following players received entry from the qualifying draw:
 * Elina Avanesyan
 * 🇪🇸 Marina Bassols Ribera
 * 🇫🇷 Léolia Jeanjean
 * 🇪🇸 Rebeka Masarova
 * 🇺🇸 Asia Muhammad
 * 🇮🇹 Matilde Paoletti

The following player received entry as a lucky loser:
 * 🇧🇷 Carolina Alves
 * 🇦🇺 Jaimee Fourlis
 * 🇦🇹 Julia Grabher

Withdrawals

 * Before the tournament
 * Kaja Juvan → replaced by 🇭🇺 Panna Udvardy
 * 🇲🇪 Danka Kovinić → replaced by Ylena In-Albon
 * Petra Martić → replaced by 🇦🇺 Jaimee Fourlis
 * Arantxa Rus → replaced by 🇷🇴 Ana Bogdan
 * 🇩🇪 Laura Siegemund → replaced by 🇦🇹 Julia Grabher
 * 🇦🇺 Ajla Tomljanović → replaced by 🇫🇷 Chloé Paquet
 * 🇮🇹 Martina Trevisan → replaced by 🇧🇷 Carolina Alves
 * During the tournament
 * 🇨🇳 Zhang Shuai

Seeds

 * † Rankings are as of 11 July 2022

Other entrants
The following pairs received wildcards into the doubles main draw:
 * 🇮🇹 Elisabetta Cocciaretto / 🇮🇹 Camilla Rosatello
 * 🇮🇹 Lisa Pigato / 🇮🇹 Lucrezia Stefanini

The following pair received entry into the doubles main draw using a special ranking:
 * 🇨🇿 Anastasia Dețiuc / 🇵🇱 Paula Kania-Choduń

The following pair received entry as alternates:
 * 🇦🇺 Jaimee Fourlis / 🇷🇴 Gabriela Lee

Withdrawals

 * Natela Dzalamidze / Kaja Juvan → replaced by  Natela Dzalamidze /  Anastasia Tikhonova
 * Ekaterine Gorgodze / Oksana Kalashnikova → replaced by 🇰🇿 Anna Danilina /  Oksana Kalashnikova
 * 🇩🇪 Laura Siegemund / 🇨🇳 Zhang Shuai → replaced by 🇨🇳 Wang Xiyu / 🇨🇳 Zhang Shuai
 * 🇮🇹 Elisabetta Cocciaretto / 🇮🇹 Camilla Rosatello → replaced by 🇦🇺 Jaimee Fourlis / 🇷🇴 Gabriela Lee