2022 Internazionali Femminili di Palermo – Doubles

Defending champion Kimberley Zimmermann and her partner, Anna Bondár, defeated Amina Anshba and Panna Udvardy in the final, 6–3, 6–2 to win the doubles tennis title at the 2022 Internazionali Femminili di Palermo. It marked Zimmermann's second career WTA Tour doubles title and Bondár's first in either discipline.

Zimmermann had won the previous edition with Erin Routliffe, who did not return to compete.

Seeds
• # Alexa Guarachi / 🇺🇸 Asia Muhammad (semifinals)

• # 🇰🇿 Anna Danilina / Oksana Kalashnikova (quarterfinals)

• # 🇭🇺 Anna Bondár / 🇧🇪 Kimberley Zimmermann (champions)

• # 🇺🇸 Ingrid Neel / 🇨🇿 Renata Voráčová (first round)