2022 Internazionali di Tennis Città di Verona – Singles

Holger Rune was the defending champion but chose not to defend his title.

Francesco Maestrelli won the title after defeating Pedro Cachin 3–6, 6–3, 6–0 in the final.

Seeds
• # 🇦🇷 Pedro Cachin (final)

• # 🇸🇰 Norbert Gombos (quarterfinals)

• # 🇮🇹 Gianluca Mager (first round)

• # 🇮🇹 Franco Agamenone (second round)

• # 🇮🇹 Flavio Cobolli (quarterfinals)

• # 🇷🇸 Nikola Milojević (first round)

• # 🇫🇷 Alexandre Müller (second round)

• # 🇮🇹 Marco Cecchinato (semifinals)