2022 L'Open 35 de Saint-Malo

The 2022 L'Open 35 de Saint-Malo was a professional tennis tournament played on outdoor clay courts. It was the twenty-seventh edition of the tournament and a part of the 2022 WTA 125 tournaments. It took place in Saint-Malo, France between 2 and 8 May 2022.

Seeds

 * 1 Rankings are as of 25 April 2022.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇫🇷 Tessah Andrianjafitrimo
 * 🇫🇷 Elsa Jacquemot
 * 🇫🇷 Léolia Jeanjean
 * Monica Puig

The following players received entry from the qualifying draw:
 * 🇫🇷 Estelle Cascino
 * 🇦🇺 Jaimee Fourlis
 * 🇯🇵 Eri Hozumi
 * 🇧🇷 Laura Pigossi

Withdrawals

 * Before the tournament
 * 🇭🇺 Anna Bondár → replaced by 🇩🇪 Tamara Korpatsch
 * 🇮🇹 Lucia Bronzetti → replaced by 🇫🇷 Océane Dodin
 * 🇫🇷 Caroline Garcia → replaced by 🇯🇵 Mai Hontama
 * Varvara Gracheva → replaced by 🇫🇷 Fiona Ferro
 * Kaja Juvan → replaced by 🇬🇧 Heather Watson
 * 🇪🇪 Kaia Kanepi → replaced by 🇨🇦 Rebecca Marino
 * 🇺🇦 Marta Kostyuk → replaced by Kamilla Rakhimova
 * 🇧🇪 Greet Minnen → replaced by 🇦🇺 Maddison Inglis
 * 🇧🇪 Alison Van Uytvanck → replaced by 🇺🇸 Bernarda Pera
 * 🇨🇳 Zheng Qinwen → replaced by 🇫🇷 Diane Parry

Seeds

 * 1 Rankings as of April 25, 2022.

Singles

 * 🇧🇷 Beatriz Haddad Maia def. Anna Blinkova 7–6(7–3), 6–3

Doubles

 * 🇯🇵 Eri Hozumi / 🇯🇵 Makoto Ninomiya def. 🇫🇷 Estelle Cascino / 🇫🇷 Jessika Ponchet 7–6(7–1), 6–1