2022 Libéma Open – Men's singles

Tim van Rijthoven defeated Daniil Medvedev in the final, 6–4, 6–1 to win the men's singles tennis title at the 2022 Rosmalen Grass Court Championships. It was his maiden ATP Tour title, and he became the first Dutchman to win an ATP Tour singles title since Robin Haase in 2012. Van Rijthoven entered the tournament as a wildcard, and he won the title by earning his first five ATP Tour wins at the tournament.

Adrian Mannarino was the defending champion from when the event was last held in 2019, but he lost in the semifinals to Medvedev.

Seeds
The top four seeds receive a bye into the second round. • # Daniil Medvedev (final)

• # 🇨🇦 Félix Auger-Aliassime (semifinals)

• # 🇺🇸 Taylor Fritz (second round)

• # 🇦🇺 Alex de Minaur (second round)

• # Karen Khachanov (quarterfinals)

• # Botic van de Zandschulp (first round)

• # 🇺🇸 Tommy Paul (first round)

• # 🇺🇸 Jenson Brooksby (second round)

Seeds
• # 🇺🇸 Sam Querrey (qualified)

• # 🇺🇸 Stefan Kozlov (first round)

• # 🇮🇹 Andreas Seppi (qualified)

• # 🇫🇷 Gilles Simon (qualified)

• # 🇦🇺 Max Purcell (first round)

• # 🇫🇷 Pierre-Hugues Herbert (qualifying competition)

• # 🇧🇪 Zizou Bergs (qualifying competition)

• # Gijs Brouwer (qualifying competition)

Qualifiers
• # 🇺🇸 Sam Querrey

• # 🇦🇺 Matthew Ebden

• # 🇮🇹 Andreas Seppi

• # 🇫🇷 Gilles Simon