2022 London Spirit season

The 2022 season was the London Spirit's second season of the 100 ball franchise cricket, The Hundred. The season was an improvement from the previous season, with the franchise reaching the knockout stages for the first time, and the men's side finishing third overall.

Men's side

 * Bold denotes players with international caps.

Women's side

 * Bold denotes players with international caps.

Fixtures (Women)
Due to the shortened women's competition, London Spirit didn't play against Manchester Originals.

Women
advances to Final advances to the Eliminator

Men
advances to Final advances to the Eliminator