2022 Louisville Cardinals men's soccer team

The 2022 Louisville Cardinals men's soccer team represented the University of Louisville during the 2022 NCAA Division I men's soccer season. The Cardinals were led by head coach John Michael Hayden, in his fourth season. They played their home games at Lynn Stadium. This was the team's 44th season playing organized men's college soccer and their 9th playing in the Atlantic Coast Conference.

The Cardinals finished the season 9–6–3 overall and 4–3–1 in ACC play to finish in third place in the Atlantic Division. As the fifth overall seed in the ACC Tournament they were upset by twelfth seed Virginia Tech in the First Round. They received an at-large bid to the NCAA Tournament where they lost in the First Round to to end their season.

Background
The Cardinals finished the season 10–7–1 overall and 5–3–0 in ACC play to finish in second place in the Atlantic Division. As the fourth overall seed in the ACC Tournament the received a bye into the Quarterfinals, where they lost against fifth seed Notre Dame. They received an at-large bid to the NCAA Tournament where they lost in the First Round to Bowling Green to end their season.

Team management
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Schedule
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!colspan=6 style=""| Regular Season

!colspan=6 style=""| ACC Tournament

!colspan=6 style=""| NCAA Tournament