2022 Makarska International Championships – Singles

Jasmine Paolini was the defending champion, but chose not to participate.

Jule Niemeier won the title, defeating Elisabetta Cocciaretto in the final, 7–5, 6–1.

Seeds
• # Varvara Gracheva (second round)

• # 🇮🇹 Lucia Bronzetti (first round)

• # Anastasia Potapova (second round)

• # 🇵🇱 Magdalena Fręch (first round)

• # 🇸🇰 Anna Karolína Schmiedlová (semifinals)

• # 🇫🇷 Clara Burel (quarterfinals)

• # 🇩🇪 Jule Niemeier (champion)

• # Ekaterine Gorgodze (first round, retired)

Seeds
• # Dalila Jakupović (qualified)

• # 🇯🇵 Eri Hozumi (qualified)

• # Mariana Dražić (qualified)

Qualifiers
• # Dalila Jakupović

• # 🇯🇵 Eri Hozumi

• # Mariana Dražić

• # Ayline Samardžić