2022 Mubadala World Tennis Championship – Men's singles

Stefanos Tsitsipas won the title, defeating the defending champion Andrey Rublev in the final.

Seeds
• # 🇪🇸 Carlos Alcaraz (semifinals) (fourth place)

• # 🇳🇴 Casper Ruud (semifinals) (third place)

• # Stefanos Tsitsipas (champion)

• # Andrey Rublev (final) (runner-up)

• # 🇬🇧 Cameron Norrie (quarterfinals) (fifth place)

• # Borna Ćorić (quarterfinals) (sixth place)