2022 National Premier Soccer League season

The 2022 National Premier Soccer League season was the 20th season of the National Premier Soccer League and part of the 110th season of FIFA-sanctioned soccer in the United States.

The regular season began on March 19 and ended on July 16. In total, 92 teams participated in this season.

Format changes
The Northwest and Southwest Conferences merged to form the Pacific Conference while the Golden Gate Conference returned to traditional league play. The Lone Star Conference returned to the South Region after temporarily joining the West in 2021.

Teams
Note: Teams that are italicized previously played in the NPSL and are returning from hiatus.

Incoming teams

 * Akron City FC (Akron, OH)
 * Apotheos FC (Kennesaw, GA)
 * Austin United FC (Austin, TX)
 * Cedar Stars FC (Chester, NY)
 * Club Atletico Saint Louis (Saint Louis, MO)
 * Corinthians FC of San Antonio (San Antonio, TX)
 * Grove Soccer United (Richmond, VA)
 * Jackson Lions FC (Jackson, NJ)
 * Lubbock Matadors SC (Lubbock, TX)
 * Magia FC (Miami Gardens, FL)
 * Miami Beach CF (Miami Beach, FL)
 * Minnesota TwinStars FC (Brooklyn Park, MN)
 * Muskegon Risers SC (Muskegon, MI)
 * Oakland SC (Oakland, CA)
 * Pennsylvania Classics AC (Lancaster, PA)
 * Philadelphia Ukrainians Nationals SC (Horsham, PA)
 * SC Brave Lions (Glendale, CA)
 * Sunflower State FC (Overland Park, KS)

Name changes

 * Greater Lowell Rough Diamonds to Alexandria Reds
 * Katy 1895 FC to CF10 Houston FC

Departing teams

 * ASC San Diego (San Diego, CA) (merged with San Diego 1904 FC and joined the National Independent Soccer Association )
 * Boston City FC (Revere, MA) (joined USL League Two )
 * FC Baltimore Christos (Baltimore, MD)
 * Metro Louisville FC (Louisville, KY) (joined United Premier Soccer League )
 * PDX FC (Portland, OR) (joined USL League Two in 2021 )
 * Rochester Lancers (Rochester, NY) (joined United Premier Soccer League )

Teams on hiatus or folded

 * Boca Raton FC (Delray Beach, FL)
 * Dallas City FC (McKinney, TX)
 * FC Golden State (Pomona, CA)
 * FC Indiana (Lafayette, IN)
 * Midland-Odessa Sockers FC (Midland, TX)
 * Port City FC (Gulfport, MS)
 * Spokane Shadow SC (Spokane, WA)
 * Storm FC (Pembroke Pines, FL)
 * Tacoma Stars (Waller, WA)
 * Temecula FC (Temecula, CA)

Pacific Conference
Due to the distance between teams, the Pacific Conference was split into two divisions. The North Division featured Crossfire Redmond, International Portland Select FC and OSA Seattle FC while the South Division included FC Arizona, Las Vegas Legends FC, and SC Brave Lions. Clubs played the other teams within their division three times each and two of the teams in the other division twice each. The top two teams from each group qualified for the playoffs and play one-another in the conference semifinals.

Playoffs
Note: Games are hosted by the highest seed unless noted otherwise

Golden Gate Conference playoffs
Bold = winner * = after extra time, = penalty shootout score

Pacific Conference playoffs
Bold = winner * = after extra time, = penalty shootout score

Gulf Coast Conference playoffs
Bold = winner * = after extra time, = penalty shootout score

Heartland Conference playoffs
Bold = winner * = after extra time, = penalty shootout score

Lone Star Conference playoffs
Bold = winner * = after extra time, = penalty shootout score

Sunshine Conference playoffs
Bold = winner * = after extra time, = penalty shootout score

Keystone Conference playoffs
Bold = winner * = after extra time, = penalty shootout score

Mid-Atlantic Conference playoffs
Bold = winner * = after extra time, = penalty shootout score

North Atlantic Conference playoffs
Bold = winner * = after extra time, = penalty shootout score

Southeast Conference playoffs
Bold = winner * = after extra time, = penalty shootout score

Regional and National playoffs
Bold = winner * = after extra time,  = penalty shootout score

2022 NPSL National Championship
Championship MVP: Coby Handy Jean Rodriguez (MOT)