2022 North Texas Mean Green football team

The 2022 North Texas Mean Green football team represented the University of North Texas as a member of Conference USA (C-USA) during the 2022 NCAA Division I FBS football season. They were led by seventh-year head coach Seth Littrell. The Mean Green played their home games at Apogee Stadium in Denton, Texas.

C-USA media day
The Conference USA media day was held on July 27 at Globe Life Field in Arlington, Texas. The Mean Green were represented by head coach Seth Littrell, tight end Jake Roberts, and linebacker K. D. Davis. The Mean Green were predicted to finish fifth in the conference's preseason poll.

Schedule
North Texas and Conference USA announced the 2022 football schedule on March 30, 2022.