2022 Open Angers Arena Loire – Singles

Vitalia Diatchenko was the defending champion but withdrew before the tournament began.

Alycia Parks won her second consecutive WTA 125K title, defeating Anna-Lena Friedsam in the final, 6–4, 4–6, 6–4.

Seeds
• # 🇨🇳 Zhang Shuai (first round)

• # 🇺🇦 Anhelina Kalinina (semifinals)

• # 🇧🇪 Alison Van Uytvanck (first round)

• # 🇩🇪 Tatjana Maria (first round)

• # 🇩🇪 Tamara Korpatsch (second round)

• # Anna Blinkova (second round)

• # 🇧🇬 Viktoriya Tomova (second round)

• # Varvara Gracheva (second round)

Seeds
• # Joanne Züger (moved into main draw)

• # 🇧🇪 Greet Minnen (qualified)

• # 🇧🇪 Magali Kempen (qualified)

• # Joanna Garland (qualified)

• # 🇱🇹 Justina Mikulskytė (first round)

• # 🇹🇷 Pemra Özgen (qualifying competition, lucky loser)

• # 🇸🇪 Caijsa Hennemann (first round)

• # 🇧🇪 Yanina Wickmayer (moved into main draw)

Qualifiers
• # 🇫🇷 Émeline Dartron

• # 🇧🇪 Greet Minnen

• # 🇧🇪 Magali Kempen

• # Joanna Garland

Lucky losers
• # 🇹🇷 Pemra Özgen

• # 🇺🇸 Hina Inoue