2022 Open Internacional de San Sebastián – Singles

This was the first edition of the tournament.

Julia Grabher won the title, defeating Aliona Bolsova in the final, 6–3, 7–6(7–3).

Seeds
• # 🇦🇹 Julia Grabher (champion)

• # 🇫🇷 Clara Burel (second round)

• # Elina Avanesyan (second round, withdrew)

• # Ekaterine Gorgodze (first round)

• # 🇦🇩 Victoria Jiménez Kasintseva (second round)

• # 🇨🇿 Brenda Fruhvirtová (quarterfinals)

• # 🇨🇾 Raluca Șerban (semifinals)

• # 🇦🇹 Sinja Kraus (first round)