2022 Open Sud de France – Singles

Alexander Bublik defeated Alexander Zverev in the final, 6–4, 6–3 to win the singles title at the 2022 Open Sud de France. It was his maiden ATP Tour title.

David Goffin was the defending champion, but lost to Adrian Mannarino in the second round.

Seeds
The top four seeds received a bye into the second round. • # 🇩🇪 Alexander Zverev (final)

• # 🇪🇸 Roberto Bautista Agut (quarterfinals)

• # 🇫🇷 Gaël Monfils (second round)

• # Nikoloz Basilashvili (second round)

• # 🇷🇸 Filip Krajinović (semifinals)

• # 🇰🇿 Alexander Bublik (champion)

• # 🇫🇷 Ugo Humbert (first round)

• # 🇧🇪 David Goffin (second round)

Seeds
• # Henri Laaksonen (first round)

• # 🇪🇸 Feliciano López (first round)

• # 🇫🇷 Pierre-Hugues Herbert (qualified)

• # 🇫🇷 Gilles Simon (qualified)

• # 🇨🇿 Jiří Lehečka (first round)

• # 🇷🇺 Roman Safiullin (qualifying competition)

• # 🇩🇪 Mats Moraing (withdrew)

• # 🇧🇦 Damir Džumhur (qualified)

Qualifiers
• # 🇵🇱 Kacper Żuk

• # 🇧🇦 Damir Džumhur

• # 🇫🇷 Pierre-Hugues Herbert

• # 🇫🇷 Gilles Simon