2022 Open Villa de Madrid – Singles

This was the first edition of the tournament.

Aliona Bolsova won the title, defeating Tamara Korpatsch in the final, 6–4, 6–2.

Seeds
• # 🇩🇪 Tamara Korpatsch (final)

• # 🇪🇸 Cristina Bucșa (second round)

• # 🇫🇷 Océane Dodin (second round)

• # 🇫🇷 Kristina Mladenovic (first round)

• # 🇵🇱 Magdalena Fręch (semifinals)

• # 🇪🇸 Rebeka Masarova (first round)

• # Ylena In-Albon (semifinals)

• # Despina Papamichail (first round)