2022 Open d'Orléans – Singles

Henri Laaksonen was the defending champion but lost in the first round to Evan Furness.

Grégoire Barrère won the title after defeating Quentin Halys 4–6, 6–3, 6–4 in the final.

Seeds
• # 🇫🇷 Corentin Moutet (second round)

• # 🇫🇷 Hugo Gaston (semifinals)

• # 🇫🇷 Richard Gasquet (quarterfinals)

• # 🇫🇷 Quentin Halys (final)

• # 🇭🇺 Márton Fucsovics (second round)

• # 🇸🇰 Norbert Gombos (quarterfinals)

• # Henri Laaksonen (first round)

• # 🇺🇸 Jack Sock (quarterfinals)