2022 Open de Tenis Ciudad de Pozoblanco – Singles

Altuğ Çelikbilek was the defending champion but lost in the first round to Alejandro Moro Cañas.

Constant Lestienne won the title after defeating Grégoire Barrère 6–0, 7–6(7–3) in the final.

Seeds
• # Nuno Borges (first round)

• # 🇫🇷 Constant Lestienne (champion)

• # 🇫🇷 Ugo Humbert (semifinals)

• # 🇫🇷 Hugo Grenier (second round)

• # 🇨🇦 Vasek Pospisil (second round)

• # 🇹🇷 Altuğ Çelikbilek (first round)

• # 🇫🇷 Grégoire Barrère (final)

• # 🇫🇷 Antoine Escoffier (quarterfinals)