2022 Orlando USTA Pro Circuit Event 2 – Singles

Zheng Qinwen was the defending champion but chose to participate at the 2022 French Open instead.

Robin Anderson won the title, defeating Sachia Vickery in the final, 7–5, 6–4.

Seeds
• # 🇺🇸 Robin Anderson (champion)

• # 🇺🇸 Grace Min (second round)

• # 🇺🇸 Jamie Loeb (second round)

• # 🇺🇸 Francesca Di Lorenzo (second round)

• # 🇦🇷 María Lourdes Carlé (quarterfinals)

• # 🇺🇸 Sachia Vickery (final)

• # 🇺🇸 Hanna Chang (first round)

• # 🇺🇸 Sophie Chang (semifinals)