2022 Porsche Tennis Grand Prix – Singles

Iga Świątek defeated Aryna Sabalenka in the final, 6–2, 6–2 to win the singles tennis title at the 2022 Women's Stuttgart Open. By winning her fourth consecutive title, Świątek extended her winning streak to 23 matches.

Ashleigh Barty was the defending champion, but she announced her retirement from professional tennis in March 2022.

Seeds
The top four seeds received a bye into the second round. • # 🇵🇱 Iga Świątek (champion)

• # 🇪🇸 Paula Badosa (semifinals)

• # Aryna Sabalenka (final)

• # Maria Sakkari (second round, retired)

• # 🇪🇪 Anett Kontaveit (quarterfinals)

• # 🇨🇿 Karolína Plíšková (second round)

• # 🇹🇳 Ons Jabeur (quarterfinals)

• # 🇬🇧 Emma Raducanu (quarterfinals)

Seeds
• # 🇭🇺 Panna Udvardy (first round)

• # 🇫🇷 Chloé Paquet (qualified)

• # 🇩🇪 Tamara Korpatsch (qualifying competition, lucky loser)

• # 🇦🇺 Maddison Inglis (first round)

• # 🇪🇸 Cristina Bucșa (first round)

• # Elina Avanesyan (qualifying competition)

• # Stefanie Vögele (qualifying competition)

• # 🇦🇺 Storm Sanders (qualified)

Qualifiers
• # 🇩🇪 Eva Lys

• # 🇫🇷 Chloé Paquet

• # 🇦🇺 Storm Sanders

• # 🇩🇪 Nastasja Schunk

Lucky loser
• # 🇩🇪 Tamara Korpatsch