2022 Prague Open

The 2022 Prague Open (branded as the 2022 Livesport Prague Open for sponsorship reasons) was a professional women's tennis tournament played on outdoor hard courts at the TK Sparta Prague. It was the 13th (WTA and non-WTA) edition of the tournament and part of the 2022 WTA Tour, classified as a WTA 250 tournament. It took place in Prague, Czech Republic from 25 to 31 July 2022. This was the second edition of the tournament held on outdoor hard courts, as opposed to clay courts in previous editions.

Singles

 * 🇨🇿 Marie Bouzková def. Anastasia Potapova, 6–0, 6–3.

This was Bouzková’s first WTA Tour singles title.

Doubles

 * Anastasia Potapova / Yana Sizikova def.  Angelina Gabueva /  Anastasia Zakharova, 6–3, 6–4

Seeds
† Rankings are as of 18 July 2022.

Other entrants
The following players received wildcard entry into the singles main draw:
 * 🇨🇿 Lucie Havlíčková
 * 🇪🇪 Anett Kontaveit
 * 🇨🇿 Linda Nosková

The following players received entry from the qualifying draw:
 * Dalila Jakupović
 * 🇨🇿 Barbora Palicová
 * 🇨🇿 Dominika Šalková
 * Oksana Selekhmeteva
 * 🇨🇳 Wang Qiang
 * Anastasia Zakharova

The following players received entry as lucky losers:
 * 🇯🇵 Nao Hibino
 * 🇦🇹 Sinja Kraus
 * Natalia Vikhlyantseva

Withdrawals

 * Before the tournament
 * Ekaterina Alexandrova → replaced by Ekaterine Gorgodze
 * Belinda Bencic → replaced by Anna Blinkova
 * 🇮🇹 Lucia Bronzetti → replaced by 🇯🇵 Nao Hibino
 * 🇬🇧 Harriet Dart → replaced by Ylena In-Albon
 * 🇫🇷 Océane Dodin → replaced by Vitalia Diatchenko
 * 🇧🇷 Beatriz Haddad Maia → replaced by 🇫🇷 Chloé Paquet
 * 🇨🇿 Petra Kvitová → replaced by 🇦🇹 Sinja Kraus
 * 🇨🇿 Karolína Muchová → replaced by Natalia Vikhlyantseva
 * Donna Vekić → replaced by 🇧🇬 Viktoriya Tomova

Seeds
† Rankings are as of 18 July 2022.

Other entrants
The following pairs received wildcard entry into the doubles main draw:
 * 🇨🇿 Lucie Havlíčková / 🇨🇿 Linda Nosková
 * 🇨🇿 Barbora Palicová / 🇨🇿 Dominika Šalková

The following pairs received entry using protected rankings:
 * 🇨🇿 Lucie Hradecká / 🇨🇿 Andrea Sestini Hlaváčková
 * 🇵🇱 Magda Linette / 🇧🇪 Yanina Wickmayer

The following pair received entry as alternates:
 * Angelina Gabueva / Anastasia Zakharova

Withdrawals

 * 🇷🇴 Irina Bara / Ekaterine Gorgodze → replaced by  Alena Fomina-Klotz /  Ekaterina Yashina
 * 🇧🇪 Kirsten Flipkens / 🇧🇪 Alison Van Uytvanck → replaced by Angelina Gabueva /  Anastasia Zakharova
 * 🇩🇪 Julia Lohoff / 🇷🇴 Laura Ioana Paar → replaced by 🇨🇿 Anastasia Dețiuc / 🇨🇿 Miriam Kolodziejová
 * 🇺🇸 Ingrid Neel / Rosalie van der Hoek → replaced by 🇺🇸 Ingrid Neel / 🇦🇺 Astra Sharma