2022 Prince Takamado U-18 Premier League

The 2022 Prince Takamado JFA U-18 Football Premier League (高円宮杯 JFA U-18サッカープレミアリーグ 2022) is the 33rd season of the main competition for under-18 teams in Japan, the 12nd after rebranding the competition to the current "Premier League" format, and the 1st season with 24 clubs participating in the league.

Aomori Yamada High School were the defending champions, winning the 2020 title. In 2021, they even qualified to the Premier League Final, but it ended up cancelled due to COVID-19 precautions.

Sagan Tosu, as West champions, faced East champions Kawasaki Frontale in the final, winning past them by 3–2. This win earned them the first Premier League title, becoming the first ever team from Saga Prefecture to do so, and the first from the Kyushu region, after Kunimi High School won it on 2002.

Participating clubs
As usual, the teams were allocated to each division by the JFA based on geographical positions. Shimizu S-Pulse was the only team to be relocated from a conference to another, having playing the previous season on the EAST conference.

Promotion/relegation play-offs
There was a difference from the 2021 edition, who awarded six direct promotions from the Prince Leagues while only two teams got relegated, to accommodate the transition from 20 to 24 teams, starting from this 2022 season.

On 2022, a total of 18 teams participated at this stage, to definitively determine all the participating teams of the posterious season. Qualified to the stage were the 16 top-ranked teams of the nine Prince League divisions and the 10th-placed teams of the East and West Premier League conferences. They were divided into six blocks, with their respective block winners (highlighted in bold) qualifying for next season's Premier League.