2022 Qatar ExxonMobil Open – Singles

Roberto Bautista Agut defeated the defending champion Nikoloz Basilashvili in a rematch of the previous year's final, 6–3, 6–4 to win the singles title at the 2022 Qatar Open.

Seeds
The top four seeds received a bye into the second round. • # 🇨🇦 Denis Shapovalov (quarterfinals)

• # 🇪🇸 Roberto Bautista Agut (champion)

• # Nikoloz Basilashvili (final)

• # Marin Čilić (quarterfinals)

• # 🇬🇧 Dan Evans (second round)

• # 🇷🇺 Karen Khachanov (semifinals)

• # 🇰🇿 Alexander Bublik (second round)

• # Lloyd Harris (first round)

Seeds
• # João Sousa (qualifying competition, lucky loser)

• # 🇸🇪 Elias Ymer (qualifying competition, lucky loser)

• # 🇦🇺 Christopher O'Connell (qualified)

• # 🇺🇦 Illya Marchenko (qualifying competition)

• # 🇺🇸 Christopher Eubanks (qualified)

• # 🇸🇰 Jozef Kovalík (qualified)

• # 🇮🇹 Thomas Fabbiano (qualified)

• # 🇷🇺 Pavel Kotov (qualifying competition)

Qualifiers
• # 🇮🇹 Thomas Fabbiano

• # 🇺🇸 Christopher Eubanks

• # 🇦🇺 Christopher O'Connell

• # 🇸🇰 Jozef Kovalík

Lucky losers
• # 🇸🇪 Elias Ymer

• # João Sousa