2022 Rancho Santa Fe Open – Singles

Rebecca Peterson was the defending champion but withdrew before her first round match.

Marcela Zacarías won the title, defeating Katrina Scott in the final, 6–1, 6–2.

Seeds
• # 🇸🇪 Rebecca Peterson (withdrew)

• # 🇨🇳 Yuan Yue (first round)

• # 🇺🇸 Katie Volynets (second round)

• # 🇯🇵 Nao Hibino (quarterfinals)

• # 🇺🇸 Caroline Dolehide (first round)

• # 🇵🇱 Katarzyna Kawa (first round)

• # 🇨🇦 Carol Zhao (first round)

• # Arianne Hartono (second round)