2022 República Dominicana Open

The 2022 República Dominicana Open was a professional tennis tournament played on green clay courts. It was the sixth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Santo Domingo, Dominican Republic between 15 and 21 August 2022.

Seeds

 * 1 Rankings were as of 8 August 2022.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇩🇴 Peter Bertran
 * 🇵🇪 Gonzalo Bueno
 * 🇩🇴 Nick Hardt

The following players received entry into the singles main draw as alternates:
 * Gonzalo Lama
 * 🇪🇨 Roberto Quiroz
 * 🇦🇷 Gonzalo Villanueva

The following players received entry from the qualifying draw:
 * 🇨🇴 Nicolás Barrientos
 * 🇧🇷 Pedro Boscardin Dias
 * 🇦🇷 Román Andrés Burruchaga
 * 🇦🇷 Facundo Juárez
 * 🇺🇸 Patrick Kypson
 * 🇨🇴 Nicolás Mejía

The following player received entry as a lucky loser:
 * 🇵🇪 Nicolás Álvarez

Singles

 * 🇦🇷 Pedro Cachin def. 🇦🇷 Marco Trungelliti 6–4, 2–6, 6–3.

Doubles

 * Ruben Gonzales / 🇺🇸 Reese Stalder def. 🇨🇴 Nicolás Barrientos / 🇲🇽 Miguel Ángel Reyes-Varela 7–6(7–5), 6–3.