2022 São Léo Open

The 2022 São Léo Open was a professional tennis tournament played on clay courts. It was the 3rd edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in São Leopoldo, Brazil between 14 and 20 November 2022.

Seeds

 * 1 Rankings are as of 7 November 2022.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇧🇷 João Fonseca
 * 🇧🇷 Gustavo Heide
 * 🇧🇷 Matheus Pucinelli de Almeida

The following players received entry into the singles main draw as alternates:
 * 🇧🇷 João Lucas Reis da Silva
 * 🇧🇷 Thiago Seyboth Wild

The following players received entry from the qualifying draw:
 * 🇧🇷 Mateus Alves
 * 🇸🇪 Leo Borg
 * Max Houkes
 * 🇧🇷 Wilson Leite
 * 🇦🇷 Juan Pablo Paz
 * Damien Wenger

The following player received entry as a lucky loser:
 * 🇧🇷 Eduardo Ribeiro

Singles

 * 🇵🇪 Juan Pablo Varillas def. 🇦🇷 Facundo Bagnis 7–6(7–5), 4–6, 6–4.

Doubles

 * 🇦🇷 Guido Andreozzi / 🇦🇷 Guillermo Durán def. 🇧🇷 Felipe Meligeni Alves / 🇧🇷 João Lucas Reis da Silva 5–1 ret.