2022 San Diego Open – Men's doubles

Nathaniel Lammons and Jackson Withrow defeated Jason Kubler and Luke Saville in the final, 7–6(7–5), 6–2 to win the doubles tennis title at the 2022 San Diego Open.

Joe Salisbury and Neal Skupski were the reigning champions, but chose not to defend their title.

Seeds
• # 🇲🇽 Santiago González / 🇦🇷 Andrés Molteni (quarterfinals)

• # 🇺🇸 Nathaniel Lammons / 🇺🇸 Jackson Withrow (champions)

• # 🇨🇴 Nicolás Barrientos / 🇲🇽 Miguel Ángel Reyes-Varela (quarterfinals)

• # 🇸🇪 André Göransson / 🇯🇵 Ben McLachlan (quarterfinals)