2022 Shymkent Challenger – Singles

Andrej Martin was the defending champion but chose not to defend his title.

Emilio Nava won the title after defeating Sebastian Fanselow 6–4, 7–6(7–3) in the final.

Seeds
• # 🇺🇸 Tennys Sandgren (first round)

• # 🇹🇷 Altuğ Çelikbilek (first round)

• # Alexander Shevchenko (second round)

• # 🇺🇦 Illya Marchenko (second round)

• # 🇪🇸 Nicolás Álvarez Varona (second round)

• # 🇯🇵 Kaichi Uchida (first round)

• # Evgeny Karlovskiy (quarterfinals)

• # 🇷🇴 Filip Jianu (first round)