2022 Silicon Valley Classic – Singles

Daria Kasatkina defeated Shelby Rogers in the final, 6–7(2–7), 6–1, 6–2 to win the singles tennis title at the 2022 Silicon Valley Classic. With the win, Kasatkina re-entered the world's Top 10 in rankings for the first time since 2019, reaching a new career high of No. 9.

Danielle Collins was the reigning champion, but withdrew before the tournament.

Seeds
The top four seeds received a bye into the second round. • # Maria Sakkari (second round)

• # 🇪🇸 Paula Badosa (semifinals)

• # 🇹🇳 Ons Jabeur (quarterfinals)

• # Aryna Sabalenka (quarterfinals)

• # 🇪🇸 Garbiñe Muguruza (withdrew)

• # 🇺🇸 Coco Gauff (quarterfinals)

• # Daria Kasatkina (champion)

• # 🇨🇿 Karolína Plíšková (second round)

• # Veronika Kudermetova (semifinals)

Seeds
• # Jil Teichmann (qualifying competition)

• # Kamilla Rakhimova (first round)

• #🇺🇸 Katie Volynets (first round)

• #🇺🇸 Alycia Parks (first round)

• #🇺🇸 Caroline Dolehide (qualifying competition, lucky loser)

• #🇺🇸 Asia Muhammad (first round)

• #🇨🇦 Carol Zhao (first round)

• #🇲🇽 Fernanda Contreras Gómez (first round)

Qualifiers
• #🇺🇸 Elizabeth Mandlik

• #🇺🇸 Taylor Townsend

• #🇺🇸 Kayla Day

• #🇦🇺 Storm Sanders

Lucky losers
• #🇺🇸 Caroline Dolehide