2022 Sofia Open – Singles

Marc-Andrea Hüsler defeated Holger Rune in the final, 6–4, 7–6(10–8) to win the singles tennis title at the 2022 Sofia Open. It was his first ATP Tour title, and he saved two match points en route, in his quarterfinal match against Kamil Majchrzak.

Jannik Sinner was the two-time defending champion, but retired from his semifinal match against Rune.

Seeds
The top four seeds received a bye into the second round. • #🇮🇹 Jannik Sinner (semifinals, retired)

• #🇪🇸 Pablo Carreño Busta (second round)

• #🇧🇬 Grigor Dimitrov (second round)

• #🇮🇹 Lorenzo Musetti (semifinals)

• # Holger Rune (final)

• # Nikoloz Basilashvili (first round)

• #🇬🇧 Jack Draper (withdrew)

• #🇩🇪 Oscar Otte (second round)

Seeds
• # 🇫🇷 Ugo Humbert (qualified)

• # 🇩🇪 Jan-Lennard Struff (qualified)

• # 🇫🇷 Geoffrey Blancaneaux (qualified)

• # 🇮🇹 Stefano Travaglia (first round, retired)

• # 🇹🇷 Altuğ Çelikbilek (first round)

• # 🇮🇹 Andreas Seppi (qualifying competition)

• # 🇮🇹 Salvatore Caruso (first round)

• # Alexey Vatutin (first round)

Qualifiers
• # 🇫🇷 Ugo Humbert

• # 🇩🇪 Jan-Lennard Struff

• # 🇫🇷 Geoffrey Blancaneaux

• # 🇸🇪 Dragoș Nicolae Mădăraș

Lucky loser
• # 🇧🇦 Mirza Bašić