2022 TCU Horned Frogs baseball team

The 2022 TCU Horned Frogs baseball team represented Texas Christian University during the 2022 NCAA Division I baseball season. The Horned Frogs played their home games at Lupton Stadium as a member of the Big 12 Conference. They were led by head coach Kirk Saarloos, in his inaugural year as head coach and tenth season at TCU.

Previous season
The 2021 TCU Horned Frogs baseball team notched a 41–20 (17–7) record. The Frogs claimed a share of the Big 12 regular season championship as well as the outright Big 12 Tournament championship. TCU received the #6 national seed in the 2021 NCAA tournament and hosted the Fort Worth Regional. The Horned Frogs were eliminated from the Tournament by cross-metroplex rival Dallas Baptist.

At the conclusion of the season, long-time TCU head coach Jim Schlossnagle departed the TCU baseball program and was replaced by 9-year assistant coach and former major league pitcher Kirk Saarloos. Saarloos retained Associate head coach Bill Mosiello, promoted John DiLaura from Volunteer Coach to Assistant Coach, retained student assistant coach and former TCU pitcher Matt Purke, and added former TCU-standout Kyle Winkler as the program's new Volunteer Assistant Coach. Winkler and Purke, both former All-American pitchers, were teammates on TCU's first-ever College World Series team in 2010.

Schedule and results
! style="" | Regular season (35–18)
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! colspan=2 |Postseason (3–4)
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 * Legend:      = Win       = Loss       = Canceled      Bold = TCU team member
 * "*" indicates a non-conference game. "#" represents ranking. All rankings from D1Baseball on the date of the contest. "" represents postseason seeding in the Big 12 Tournament or NCAA Regional, respectively.
 * Legend:      = Win       = Loss       = Canceled      Bold = TCU team member
 * "*" indicates a non-conference game. "#" represents ranking. All rankings from D1Baseball on the date of the contest. "" represents postseason seeding in the Big 12 Tournament or NCAA Regional, respectively.
 * "*" indicates a non-conference game. "#" represents ranking. All rankings from D1Baseball on the date of the contest. "" represents postseason seeding in the Big 12 Tournament or NCAA Regional, respectively.