2022 Teréga Open Pau–Pyrénées – Singles

Radu Albot was the defending champion but lost in the second round to Antoine Escoffier.

Quentin Halys won the title after defeating Vasek Pospisil 4–6, 6–4, 6–3 in the final.

Seeds
• # 🇫🇷 Benjamin Bonzi (withdrew)

• # 🇫🇷 Richard Gasquet (withdrew)

• # 🇨🇿 Jiří Lehečka (first round)

• # 🇫🇷 Pierre-Hugues Herbert (second round)

• # 🇸🇰 Norbert Gombos (first round)

• # 🇫🇷 Gilles Simon (quarterfinals)

• # 🇫🇷 Quentin Halys (champion)

• # 🇨🇦 Vasek Pospisil (final)